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1- Department of General Surgical Diseases, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
2- Cardiovascular Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.
3- Faculty of Medicine, Tehran Islamic Azad University of Medical Sciences, Tehran, Iran.
4- Faculty of Medicine, Tehran Islamic Azad University of Medical Sciences, Tehran, Iran. ,shojaee7@gmail.com
2- Cardiovascular Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.
3- Faculty of Medicine, Tehran Islamic Azad University of Medical Sciences, Tehran, Iran.
4- Faculty of Medicine, Tehran Islamic Azad University of Medical Sciences, Tehran, Iran. ,
Abstract: (39 Views)
Objectives: Basal cell carcinoma (BCC) is the most common cutaneous malignancy, with a rising incidence in the aging population. This study aimed to evaluate the safety of Mohs micrographic surgery in older patients with basal cell carcinoma and to assess factors associated with postoperative complications.
Materials and Methods: In this retrospective descriptive–analytical study, medical records of older patients (≥65 years) who underwent MMS for BCC between 2022 and 2025 in Farhikhtegan hospital were reviewed. Demographic data, tumor characteristics, surgical and reconstructive methods, comorbidities (diabetes mellitus and hypertension), aspirin use, and postoperative complications within a one-month follow-up period were collected. Statistical analyses were performed using Python programming language version 3 and Chi square and Independent sample t- tests.
Results: A total of 117 older patients with means 74.15±6/36 were included, while 74(63.2%) of these patients were male and 43(36.8%) female. Postoperative complications occurred in 6 patients. The most common complications were delayed wound healing and partial flap or graft necrosis. No cases of postoperative bleeding were observed. There was no statistically significant association between postoperative complications and age, sex, tumor size or location, reconstructive method (flap or graft), diabetes mellitus, hypertension, or aspirin use (p > 0.05).
Conclusion: Mohs micrographic surgery appears to be a safe and well-tolerated treatment for basal cell carcinoma in older patients, with a low rate of postoperative complications. Advanced age, common comorbidities, and aspirin use were not associated with an increased risk of complications in this cohort. These findings support the use of MMS as a reliable surgical option for older patients with BCC.
Materials and Methods: In this retrospective descriptive–analytical study, medical records of older patients (≥65 years) who underwent MMS for BCC between 2022 and 2025 in Farhikhtegan hospital were reviewed. Demographic data, tumor characteristics, surgical and reconstructive methods, comorbidities (diabetes mellitus and hypertension), aspirin use, and postoperative complications within a one-month follow-up period were collected. Statistical analyses were performed using Python programming language version 3 and Chi square and Independent sample t- tests.
Results: A total of 117 older patients with means 74.15±6/36 were included, while 74(63.2%) of these patients were male and 43(36.8%) female. Postoperative complications occurred in 6 patients. The most common complications were delayed wound healing and partial flap or graft necrosis. No cases of postoperative bleeding were observed. There was no statistically significant association between postoperative complications and age, sex, tumor size or location, reconstructive method (flap or graft), diabetes mellitus, hypertension, or aspirin use (p > 0.05).
Conclusion: Mohs micrographic surgery appears to be a safe and well-tolerated treatment for basal cell carcinoma in older patients, with a low rate of postoperative complications. Advanced age, common comorbidities, and aspirin use were not associated with an increased risk of complications in this cohort. These findings support the use of MMS as a reliable surgical option for older patients with BCC.
Keywords: Basal cell carcinoma, Mohs micrographic surgery, older, Postoperative complications, Skin cancer
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