Volume 13, Issue 4 (Winter 2019)                   Salmand: Iranian Journal of Ageing 2019, 13(4): 506-517 | Back to browse issues page

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Hejazi K, Ghahremani Moghaddam M, Darzabi T. Effects of an 8-Week Aerobic Exercise Program on Some Indicators of Oxidative Stress in Elderly Women. Salmand: Iranian Journal of Ageing. 2019; 13 (4) :506-517
URL: http://salmandj.uswr.ac.ir/article-1-1271-en.html
1- Department of Physical Education, Toos Institute of Higher Education, Mashhad, Iran. , keyvanhejazi@gmail.com
2- Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
3- Department of Vocational Science, Faculty Technical of Shahid Montazeri, Technical and Vocational University, Mashhad, Iran.
Abstract:   (1324 Views)

Objectives Oxidative stress has an important role in the pathogenesis of diseases such as cardiovascular disease, cancer, diabetes and aging. The present study investigated the effects of 8 weeks of aerobic training on 8-hydroxy-2′-deoxyguanosine and body composition in elderly women.
Methods & Materials This was a quasi-experimental study. The study participants were selected by convenience sampling method. In total, 21 subjects with the age range of 60-70 years were assigned into 2 groups (experimental [n=11] and control [n=10]). The 8-week aerobic training program were demonstrated 3 sessions a week, for 45-60 minutes per session, with the intensity of 50% to 70% of maximum heart rate. The blood samples were obtained 24 hours after the intervention to measure the serum levels of 8-OHdG. For comparison of within and between group mean scores, Paired t test and Independent samples t test were used, respectively.
Results Eight weeks aerobic training significantly reduced the weight, BMI and body fat percentage in elderly women. Moreover, the levels of serum 8-OHdG after an 8 weeks aerobic training significantly reduced. However, the levels of 8-OHdG urine reduced at the end of the training, but it was non-significant. There were significant differences between active and inactive elderly woman in terms of weight and serum 8-OHdG variables.
Conclusion This study suggests that aerobic training decreases serum 8-OHdG. Regular aerobic physical activity with moderate intensity improves the body anti-oxidative capacity and can prevent the incidence of atherosclerosis disease.

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Type of Study: Research | Subject: General
Received: 2018/08/01 | Accepted: 2018/10/17 | Published: 2019/01/01

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