Volume 13, Issue 5 (Special Issue 2019)                   Salmand: Iranian Journal of Ageing 2019, 13(5): 534-549 | Back to browse issues page


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Ahmadi Ahangar A, Saadat P, Hosseini S R, Bijani A, Samaei S E, Mostafazadeh Bora M et al . Relationship of Serum Lipid Levels and Other Underlying Factors With Cognitive Impairment in the Elderly. Salmand: Iranian Journal of Ageing 2019; 13 (5) :534-549
URL: http://salmandj.uswr.ac.ir/article-1-1543-en.html
1- Movement Disorder Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
2- Department of Internal Medicine, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
3- Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
4- Clinical Research Development Unit, Rohani Hospital, Babol University of Medical Sciences, Babol, Iran.
5- Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. , mandanakalantari90@gmail.com
Abstract:   (16591 Views)
Objectives The involvement of factors such as serum lipids and lipoproteins concentration has been reported as a potential risk factor for cognitive impairment. This study aimed to investigate the effect of underlying factors and serum lipid levels on cognitive impairment in the elderly.
Methods & Materials This cross-sectional study was conducted on 1519 elderly in Amirkola City by the census method, from September 2016 to March 2017 (6 months). The data collection tools were a background information form of older adults and the mini-mental state exam. The obtained data were analyzed in SPSS version 23 using descriptive statistics and inferential statistics such as the Kolmogorov-Smirnov test, the Chi-squared test, analysis of variance (1-way ANOVA) and Tukey’s post hoc test.
Results According to the results, 9% (13 elderly) of the study population had severe cognitive impairment. The results of the Chi-square test did not show a significant relationship between gender and cognitive impairment (P>0.05). The significant differences were found between age, blood pressure, total cholesterol, and low-density lipoproteins variables with the categorized groups of cognitive impairments of the elderly (P≤0.05). 
Conclusion Screening for cognitive impairments is one of the recommendations of this study. Early diagnosis and treatment of this disease, especially in high-risk groups such as women and elderly with hypertension and disrupted serum lipid profile can play an important role in controlling the disease and reducing the care burden.
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Type of Study: Research | Subject: General
Received: 2018/03/10 | Accepted: 2018/10/20 | Published: 2019/03/10

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