Volume 19, Issue 3 (Autumn 2024)
Salmand: Iranian Journal of Ageing 2024, 19(3): 470-483 |
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Salehi N, Abasi F, Mahmoudi Bavandpouri S, Motevaseli S. Predictors of One-year Mortality in Older Patients With Myocardial Infarction: Results of a Cohort Study. Salmand: Iranian Journal of Ageing 2024; 19 (3) :470-483
URL: http://salmandj.uswr.ac.ir/article-1-2718-en.html
URL: http://salmandj.uswr.ac.ir/article-1-2718-en.html
1- Cardiovascular Research Center, Health Research Institute, Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
2- Deputy of Research and Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
3- Student Research Committee, Kermanshah University of Medical Sciences Kermanshah Iran. ,sayemotevaseli@gmail.com
2- Deputy of Research and Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
3- Student Research Committee, Kermanshah University of Medical Sciences Kermanshah Iran. ,
Abstract: (1301 Views)
Objectives Little is known about the mortality rate of ST-segment elevation myocardial infarction (STEMI) in older people form low- and middle-income countries. Therefore, this study aims to investigate the predictors of one-year mortality in older people with STEMI in Kermanshah, Iran.
Methods & Materials This is a cohort study that was conducted on 421 older patients with STEMI admitted to Imam-Ali Hospital in Kermanshah from July 3, 2018, to December 21, 2019. Descriptive statistics were used to report the risk factors, and univariate and multiple Cox proportional-hazards model were used to investigate predictors of one-year mortality.
Results The patients had a mean age of 73.51±6.73 years. The majority of them were male (67.5%), residents of Kermanshah (74.9%), and illiterate (60.8%). Reperfusion therapy was administered for 86.0% of patients (50.4% with percutaneous coronary intervention [PCI] and 30.4% with thrombolytic treatment). The follow-up period was 350.62 person-years. In one year, 76 patients (18.5%) died, of whom 12.4% had PCI, 16.1% thrombolytic treatment, and 0.38% no reperfusion therapy. Independent predictors of mortality were: No reperfusion therapy (hazard ratio [HR]: 2.42, 95% CI, 1.14%, 5.11%) and glomerular filtration rate (HR:0.97, 95% CI, 0.94%, 0.99%).
Conclusion In this study, the older patients with STEMI treated by PCI had a lower one-year mortality rate. It is recommended to establish a comprehensive STEMI network to enhance timely reperfusion for these patients and improve their health literacy.
Methods & Materials This is a cohort study that was conducted on 421 older patients with STEMI admitted to Imam-Ali Hospital in Kermanshah from July 3, 2018, to December 21, 2019. Descriptive statistics were used to report the risk factors, and univariate and multiple Cox proportional-hazards model were used to investigate predictors of one-year mortality.
Results The patients had a mean age of 73.51±6.73 years. The majority of them were male (67.5%), residents of Kermanshah (74.9%), and illiterate (60.8%). Reperfusion therapy was administered for 86.0% of patients (50.4% with percutaneous coronary intervention [PCI] and 30.4% with thrombolytic treatment). The follow-up period was 350.62 person-years. In one year, 76 patients (18.5%) died, of whom 12.4% had PCI, 16.1% thrombolytic treatment, and 0.38% no reperfusion therapy. Independent predictors of mortality were: No reperfusion therapy (hazard ratio [HR]: 2.42, 95% CI, 1.14%, 5.11%) and glomerular filtration rate (HR:0.97, 95% CI, 0.94%, 0.99%).
Conclusion In this study, the older patients with STEMI treated by PCI had a lower one-year mortality rate. It is recommended to establish a comprehensive STEMI network to enhance timely reperfusion for these patients and improve their health literacy.
Type of Study: Research |
Subject:
Geriatric
Received: 2023/10/16 | Accepted: 2023/12/24 | Published: 2024/10/01
Received: 2023/10/16 | Accepted: 2023/12/24 | Published: 2024/10/01
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