Volume 19, Issue 3 (Autumn-In Press 2024)
Salmand: Iranian Journal of Ageing 2024, 19(3): 0-0 |
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Salehi N, Abasi F, Mahmoudi Bavandpouri S, Motevaseli S. Predictors of One-Year Mortality in Elderly Patients with ST-Segment Elevation Myocardial Infarction Imam-Ali Hospital (2018-2019): The Results of a Cohort Study. Salmand: Iranian Journal of Ageing 2024; 19 (3)
URL: http://salmandj.uswr.ac.ir/article-1-2718-en.html
URL: http://salmandj.uswr.ac.ir/article-1-2718-en.html
1- Cardiovascular Research Center, Research Institute for Health, Imam Ali Hospital Kermanshah University of Medical Sciences Kermanshah, Iran.
2- Deputy of research and technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
3- Cardiovascular Research Center, Research Institute for Health, Imam Ali Hospital Kermanshah University of Medical Sciences Kermanshah, Iran. ,sayemotevaseli@gmail.com
2- Deputy of research and technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
3- Cardiovascular Research Center, Research Institute for Health, Imam Ali Hospital Kermanshah University of Medical Sciences Kermanshah, Iran. ,
Abstract: (765 Views)
Background: Little is known about the elderly population with ST-segment elevation myocardial infarction (STEMI) in low- and middle-income countries. Therefore, our aim was to investigate the predictors of one-year mortality of elderly STEMI patients in Kermanshah City.
Method: This cohort study was conducted on 421 elderly STEMI patients who were admitted to Imam-Ali Hospital in Kermanshah between July 3, 2018, and December 21, 2019. Descriptive statistics were used to investigate the prevalence of risk factors, and univariate and multiple Cox regression models were used to investigate predictors of one-year mortality in the elderly.
Result: The study involved 421 elderly individuals with STEMI, with an average age of 73.51 ± 6.73. The majority of patients were men (67.5%), residents of Kermanshah (74.9%), and illiterate (60.8%). Reperfusion therapy was administered for 86.0% of patients (percutaneous coronary intervention(PCI):50.4%, thrombolytic:30.4%). The follow-up period was 350.62 person-years. In one year 76 elderly people (18.5%) died, of which 12.4% had undergone PCI treatment, 16.1% had undergone thrombolytic treatment, and 0.38% had not received reperfusion therapy. Independent predictors of mortality were: no reperfusion therapy (HR: 2.42, 95% CI:1.14-5.11), and glomerular filtration rate (HR:0.97, 95% CI:0.94-0.99).
Conclusion: The findings show that reperfusion therapy is an effective treatment that leads to a better prognosis for the elderly. In particular, the elderly treated with PCI showed a lower one-year mortality rate. It is recommended to establish a comprehensive STEMI network to enhance timely reperfusion for patients and to develop plans for improving the health literacy of the elderly.
Method: This cohort study was conducted on 421 elderly STEMI patients who were admitted to Imam-Ali Hospital in Kermanshah between July 3, 2018, and December 21, 2019. Descriptive statistics were used to investigate the prevalence of risk factors, and univariate and multiple Cox regression models were used to investigate predictors of one-year mortality in the elderly.
Result: The study involved 421 elderly individuals with STEMI, with an average age of 73.51 ± 6.73. The majority of patients were men (67.5%), residents of Kermanshah (74.9%), and illiterate (60.8%). Reperfusion therapy was administered for 86.0% of patients (percutaneous coronary intervention(PCI):50.4%, thrombolytic:30.4%). The follow-up period was 350.62 person-years. In one year 76 elderly people (18.5%) died, of which 12.4% had undergone PCI treatment, 16.1% had undergone thrombolytic treatment, and 0.38% had not received reperfusion therapy. Independent predictors of mortality were: no reperfusion therapy (HR: 2.42, 95% CI:1.14-5.11), and glomerular filtration rate (HR:0.97, 95% CI:0.94-0.99).
Conclusion: The findings show that reperfusion therapy is an effective treatment that leads to a better prognosis for the elderly. In particular, the elderly treated with PCI showed a lower one-year mortality rate. It is recommended to establish a comprehensive STEMI network to enhance timely reperfusion for patients and to develop plans for improving the health literacy of the elderly.
Type of Study: Research |
Subject:
Geriatric
Received: 2023/10/16 | Accepted: 2023/12/24 | Published: 2024/10/10
Received: 2023/10/16 | Accepted: 2023/12/24 | Published: 2024/10/10
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