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1- Islamic Azad university ,
Abstract:   (764 Views)

Objectives: Obesity is directly associated with increased risk of breast cancer in postmenopausal women. The aim of this study was to examine the effect of aerobic training at moderate intensity on some biomarkers of breast cancer in overweight postmenopausal women.  

Methods and Materials: Twenty four overweight postmenopausal women (BMI, 32.01±5.3 kg/m2) with mean age of 55.44±4.4 years randomly divided into experimental (n=14) and control (n=10) groups. Subjects of experimental group were performed 10 weeks of aerobic training (3 sessions per week with 65-75% MHR). Control group did not participate in any exercise training. Sex hormone-binding globulin and insulin levels, insulin resistance, body fat percent and vo2max measured at the beginning and after training. Data were analyzed by analysis of covariance   using SPSS statistical software version 16.

Results: No significant difference was observed in sex hormone-binding globulin, insulin, insulin resistance and body fat percent after 10 weeks of aerobic training; however significant difference was found in vo2max between two groups.

Conclusions: Short-term moderate-intensity aerobic training appears to have no effects on some biomarkers of breast cancer such as sex hormone-binding globulin, insulin and insulin resistance in overweight postmenopausal women. Therefore further studies are recommended to evaluate the effectiveness of training programs with different intensities and durations.

Full-Text [PDF 1838 kb]   (233 Downloads)    
Type of Study: Research | Subject: General
Received: 2018/03/08 | Accepted: 2018/10/06

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