Objectives: The purpose of this study was to consider the effect of eight weeks aerobic training on PTH, albumin, calcium, alkaline phosphatesand estrogen levels in postmenopausal women.

Methods & Materials: 22 postmenopause women, 55-70 years, of Jahandidegan center in Tehran were selected and randomly divided into two groups: [experimental (12) and control (10)]. They had aerobic training program included 8 weeks jogging and aerobic movement with 60-70% MHR intensity, 3 times per week. Fasting blood samples were collected 24 hour before and after training. Serum PTH and estradiol were measured by an enzyme link immonosorbent assay (ELISA). Serum calcium was estimated by using photometric test (CPC), Serum ALP was measured by using kinetic photometric test. Independed and paired ttest were used to analyze data.

Results: The results showed that PTH and alkaline phosphates increased significantly after aerobic training (P≤0.05). Calcium and albuminconcentration decreased but not significantly (P≥0.05). Estrogen concentration did not significantly (P≥0.05) decrease.

Conclusion: Increased PTH and alkaline phosphates concentrations, along with nonsignificant decrease in estrogen level seem to promote anabolic process of bone formation. The result of this study supports the possible positive effect of physical activity on bone metabolism.