Objectives: during the last two decades , Activities concerning demand reduction and specially addict’s treatment and rehab have outstandingly improved in Iran. Now different treatment alternatives such as outpatient and residential care centers such as‚ abstinence based and spiritual therapies like, narcotic anonymous are developed. Treatment program in human recovery population is replacing opium tincture and gradually reduction of it (during 11 month). And it includes group and spiritual therapies.

Methods & Materials: this research is a descriptive study which has been done cohort and longitudinal during 3 months (from the beginning’ one and three months after entrance). In this research, the quality of life has been assessed. Participants include all addicts over 40 who have referred to the society (congress 60) for detoxification. Choosing the samples has been based on the method of accessible sampling. Demographic questionnaire and life quality questionnaire have been collecting information tools. Data’s have been analyzed by software spss.

Results: out of 33 people, 15 were over 50 years old. The substance abused include: Opium abuse With the frequency of 12 people (36.4%) ‚heroin crack with the frequency of 14 people (42.2%) had the most frequency. Monthly cost of drug abusing is on average 159/849 toomans, for each person. for all subscales of life quality, P-value has been reported below 0.05.

Conclusion: Detoxification has been effective in improving quality of life. just for the two following questions the persons opinion has not changed during three periods: "it seems that I get diseases easier than others" and my health is the same as other people I know". it can be said perhaps short period treatments have little influence on the change of "ones deep attitude towards himself" and a deep, essential change of attitude needs long period rehabilitation programs.