Volume 15, Issue 4 (Winter - In Press 2021)                   Salmand: Iranian Journal of Ageing 2021, 15(4): 4-4 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Dadashihaji A, Rahimi A, Hosseini S R, Moghadamnia A A, Bijani A. Inappropriate Medication Use in The Elderly of Amir Kola and Related Factors. Salmand: Iranian Journal of Ageing. 2021; 15 (4) :4-4
URL: http://salmandj.uswr.ac.ir/article-1-2059-en.html
1- Babol University of Medical Sciences
2- Babol University of Medical Sciences, Babol, Iran. , atena.rahimi@yahoo.com
3- Babol University of Medical Sciences, Babol, Iran.
Abstract:   (590 Views)
Background: Due to the inappropriate drug use by the elderly leading to adverse drug reactions and side effects, this study aimed to determine the rate of inappropriate medication use among the elderly of Amirkola city using the Beers criteria.
Methods: This descriptive and analytical study is part of a comprehensive study of "AHAP Elderly Health Status Study" (No. 892917) which was performed as a cohort study on all persons 60 years and older in Amirkola city in northern Iran. Required data were collected by a trained person using standard questionnaires. The data were collected by self-report and by observing the patientchr('39')s medications used, including the number, type and duration of drug use.
Results: The mean age of the elderly was 69.71 ± 7.47 years. Prevalence of inappropriate drug use and drugs that should use by caution among the elderly was 37.58% and 29.85%, respectively. The most inappropriate drugs use was glibenclamide (12.7%), diclofenac (8.8%) and clidinium C (5.4%). The highest rate of drug-drug interaction was due to the use of two anticholinergic drugs together. There was a statistically significant relationship between inappropriate drug use with age, education level, occupational status, and marital status and number of underlying diseases (p˂0.001, p = 0.036, p˂0.001, and p = 0.044 respectively).
Conclusion: The rate of inappropriate drug use among the elderly of Amirkola city is high compared to many other studies, which exposes the elderly to adverse drug reactions.
     
Type of Study: Research | Subject: Pharmacy
Received: 2020/07/15 | Accepted: 2020/11/29 | Published: 2021/02/24

References
1. Lim Y-J, Kim H-Y, Choi J, Lee JS, Ahn A-L, Oh E-J, et al. Potentially inappropriate medications by beers criteria in older outpatients: prevalence and risk factors. Korean journal of family medicine. 2016;37(6):329. [DOI:10.4082/kjfm.2016.37.6.329] [PMID] [PMCID]
2. Nishtala PS, Narayan SW, Wang T, Hilmer SN. Associations of drug burden index with falls, general practitioner visits, and mortality in older people. Pharmacoepidemiology and drug safety. 2014;23(7):753-8. [DOI:10.1002/pds.3624] [PMID]
3. Al-Azayzih A, Alamoori R, Altawalbeh SM. Potentially inappropriate medications prescribing according to Beers criteria among elderly outpatients in Jordan: a cross sectional study. Pharmacy Practice (Granada). 2019;17(2). [DOI:10.18549/PharmPract.2019.2.1439] [PMID] [PMCID]
4. Grina D, Karpavičiūtė J, Minkutė R, Briedis V. Impact of hospitalization on potentially inappropriate prescribing: a cross-sectional study in an acute geriatric hospital in Lithuania. International Journal of Clinical Pharmacy. 2020:1-8. [DOI:10.1007/s11096-020-01035-y] [PMID]
5. Chang CM, Liu PYY, Yang YHK, Yang YC, Wu CF, Lu FH. Use of the Beers criteria to predict adverse drug reactions among first‐visit elderly outpatients. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2005;25(6):831-8. [DOI:10.1592/phco.2005.25.6.831] [PMID]
6. Perri III M, Menon AM, Deshpande AD, Shinde SB, Jiang R, Cooper JW, et al. Adverse outcomes associated with inappropriate drug use in nursing homes. Annals of Pharmacotherapy. 2005;39(3):405-11. [DOI:10.1345/aph.1E230] [PMID]
7. Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC. Explicit criteria for determining inappropriate medication use in nursing home residents. Archives of internal medicine. 1991;151(9):1825-32. https://doi.org/10.1001/archinte.1991.00400090107019 [DOI:10.1001/archinte.151.9.1825] [PMID]
8. Awad A, Hanna O. Potentially inappropriate medication use among geriatric patients in primary care setting: A cross-sectional study using the Beers, STOPP, FORTA and MAI criteria. PloS one. 2019;14(6):e0218174. [DOI:10.1371/journal.pone.0218174] [PMID] [PMCID]
9. Christopher A, Pranita V, Mathews KP, Surekha V, Gopinath K, Gowri M. Potentially Inappropriate Medication use in the Elderly in a Tertiary Care Centre in South India. Journal of the Indian Academy of Geriatrics. 2018;14(3). [DOI:10.35262/jiag.v14i3.130-135]
10. Davidoff AJ, Miller GE, Sarpong EM, Yang E, Brandt N, Fick DM. Prevalence of potentially inappropriate medication use in older adults using the 2012 Beers criteria. Journal of the American Geriatrics Society. 2015;63(3):486-500. [DOI:10.1111/jgs.13320] [PMID] [PMCID]
11. Vali L, Pour Reza A, Rahimi Foroushani A, Ahmadi B, Akbari Kamrani AA. Analysis of Inappropriate Medication Use in Older Adults Discharged From Hospitals Affiliated With Tehran University of Medical Sciences (TUMS) Using the Beers Criteria in 2010. Salmand: Iranian Journal of Ageing. 2011;6(3):56-65.
12. Heidari S, Aliabadi A, Naebi A, Khoramirad A. Frequency of Use of Potentially Inappropriate Medications and Its Associated Factors in Elderly People in Qom City, 2012, Iran. Qom Univ Med Sci J. 2014;8(4):44-52.
13. Hosseini SR, Bayani MA, Mohammadi K, Mohammadi E, Bijani A. Correlation between anthropometric indexes and risk factors of cardiovascular diseases among the elderly population in Amirkola. Feyz Journal of Kashan University of Medical Sciences. 2017;21(3):272-9.
14. Campanelli CM. American Geriatrics Society updated beers criteria for potentially inappropriate medication use in older adults: the American Geriatrics Society 2012 Beers Criteria Update Expert Panel. Journal of the American Geriatrics Society. 2012;60(4):616. [DOI:10.1111/j.1532-5415.2012.03923.x] [PMID] [PMCID]
15. Niwata S, Yamada Y, Ikegami N. Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities. BMC geriatrics. 2006;6(1):1. [DOI:10.1186/1471-2318-6-1] [PMID] [PMCID]
16. Raji MA, Ostir GV, Markides KS, Espino DV, Goodwin JS. Potentially inappropriate medication use by elderly Mexican Americans. Annals of Pharmacotherapy. 2003;37(9):1197-202. [DOI:10.1345/aph.1C480] [PMID]
17. Andrews H, Betz M, Chihuri S, DiGuiseppi C, Eby D, Gordon A, et al. Prevalence of Potentially Inappropriate Medication Use in Older Drivers: AAA LongROAD Study. 2018.
18. Miller GE, Sarpong EM, Davidoff AJ, Yang EY, Brandt NJ, Fick DM. Determinants of potentially inappropriate medication use among community‐dwelling older adults. Health services research. 2017;52(4):1534-49. [DOI:10.1111/1475-6773.12562] [PMID] [PMCID]
19. Blozik E, Rapold R, von Overbeck J, Reich O. Polypharmacy and potentially inappropriate medication in the adult, community-dwelling population in Switzerland. Drugs & aging. 2013;30(7):561-8. [DOI:10.1007/s40266-013-0073-0] [PMID]
20. Fialová D, Topinková E, Gambassi G, Finne-Soveri H, Jónsson PV, Carpenter I, et al. Potentially inappropriate medication use among elderly home care patients in Europe. Jama. 2005;293(11):1348-58. [DOI:10.1001/jama.293.11.1348] [PMID]
21. Nightingale G, Hajjar E, Swartz K, Andrel-Sendecki J, Chapman A, editors. Evaluation of a pharmacist-led medication assessment used to identify prevalence of and associations with polypharmacy and potentially inappropriate medication use among ambulatory senior adults with cancer2015: American Society of Clinical Oncology. [DOI:10.1200/JCO.2014.58.7550] [PMID]
22. Wessell AM, Nietert PJ, Jenkins RG, Nemeth LS, Ornstein SM. Inappropriate medication use in the elderly: results from a quality improvement project in 99 primary care practices. The American journal of geriatric pharmacotherapy. 2008;6(1):21-7. [DOI:10.1016/j.amjopharm.2008.02.001] [PMID]
23. Lai H-Y, Hwang S-J, Chen Y-C, Chen T-J, Lin M-H, Chen L-K. Prevalence of the prescribing of potentially inappropriate medications at ambulatory care visits by elderly patients covered by the Taiwanese National Health Insurance program. Clinical therapeutics. 2009;31(8):1859-70. [DOI:10.1016/j.clinthera.2009.08.023] [PMID]
24. Ghadimi H, Esmaily HM, Wahlstrom R. General practitioners' prescribing patterns for the elderly in a province of Iran. Pharmacoepidemiology and drug safety. 2011;20(5):482-7. [DOI:10.1002/pds.2106] [PMID]
25. de Oliveira Baldoni A, Ayres LR, Martinez EZ, Dewulf NdLS, dos Santos V, Pereira LRL. Factors associated with potentially inappropriate medications use by the elderly according to Beers criteria 2003 and 2012. International journal of clinical pharmacy. 2014;36(2):316-24. [DOI:10.1007/s11096-013-9880-y] [PMID]
26. Goulding MR. Inappropriate medication prescribing for elderly ambulatory care patients. Archives of internal medicine. 2004;164(3):305-12. [DOI:10.1001/archinte.164.3.305] [PMID]
27. Alhmoud E, Khalifa S, Bahi AA. Prevalence and predictors of potentially inappropriate medications among home care elderly patients in Qatar. International journal of clinical pharmacy. 2015;37(5):815-21. [DOI:10.1007/s11096-015-0125-0] [PMID]
28. Dhalla IA, Anderson GM, Mamdani MM, Bronskill SE, Sykora K, Rochon PA. Inappropriate prescribing before and after nursing home admission. Journal of the American Geriatrics Society. 2002;50(6):995-1000. [DOI:10.1046/j.1532-5415.2002.50252.x] [PMID]
29. Onder G, Landi F, Cesari M, Gambassi G, Carbonin P, Bernabei R. Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly. European journal of clinical pharmacology. 2003;59(2):157-62. [DOI:10.1007/s00228-003-0600-8] [PMID]
30. Cannon KT, Choi MM, Zuniga MA. Potentially inappropriate medication use in elderly patients receiving home health care: a retrospective data analysis. The American journal of geriatric pharmacotherapy. 2006;4(2):134-43. [DOI:10.1016/j.amjopharm.2006.06.010] [PMID]
31. Vanier A, Paille C, Abbey H, Berrut G, Lombrail P, Moret L. Assessment of inappropriate prescribing in the elderly subject during acute care hospitalisation. Gériatrie et Psychologie Neuropsychiatrie du Vieillissement. 2011;9(1):51-7. [DOI:10.1684/pnv.2011.0256] [PMID]
32. Zhang Y-J, Liu W-W, Wang J-B, Guo JJ. Potentially inappropriate medication use among older adults in the USA in 2007. Age and ageing. 2011;40(3):398-401. [DOI:10.1093/ageing/afr012] [PMID]
33. Oliveira MG, Amorim WW, de Jesus SR, Rodrigues VA, Passos LC. Factors associated with potentially inappropriate medication use by the elderly in the Brazilian primary care setting. International journal of clinical pharmacy. 2012;34(4):626-32. [DOI:10.1007/s11096-012-9656-9] [PMID]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2021 All Rights Reserved | Iranian Journal of Ageing

Designed & Developed by : Yektaweb