Volume 21, Issue 1 (Spring- In Press 2026)
Salmand: Iranian Journal of Ageing 2026, 21(1): 44-61 |
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Heydari kharaji Z, Safari F, Hemati Farsani Z, Habibi Ghahfarrokhi S, Fallahzadeh H. Effect of Aerobic Exercise Timing on Fatty Liver Markers in Older Women With Type 2 Diabetes. Salmand: Iranian Journal of Ageing 2026; 21 (1) :44-61
URL: http://salmandj.uswr.ac.ir/article-1-3012-en.html
URL: http://salmandj.uswr.ac.ir/article-1-3012-en.html
Zahra Heydari kharaji1 
, Fatemeh Safari2 , Zahra Hemati Farsani *3 , Shahrzad Habibi Ghahfarrokhi4 , Hossein Fallahzadeh5
, Fatemeh Safari2 , Zahra Hemati Farsani *3 , Shahrzad Habibi Ghahfarrokhi4 , Hossein Fallahzadeh5
1- Department of Geriatric, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Department of Physiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Department of Sport Sciences, Faculty of Humanities and Social Sciences, Ardakan University, Ardakan, Iran. ,zhemati@ardakan.ac.ir
4- Department of Social Medicine, Social Determinants of Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
5- Department of Biostatistics and Epidemiology, Research Center for Healthcare Data Modeling, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2- Department of Physiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
3- Department of Sport Sciences, Faculty of Humanities and Social Sciences, Ardakan University, Ardakan, Iran. ,
4- Department of Social Medicine, Social Determinants of Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
5- Department of Biostatistics and Epidemiology, Research Center for Healthcare Data Modeling, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (1855 Views)
Objectives Type 2 diabetes is one of the most common metabolic diseases, especially prevalent in the elderly, and carries numerous complications, including an increased risk of liver diseases, such as non-alcoholic fatty liver disease (NAFLD).. The aim of this study was to determine the effect of aerobic exercise in two phases of light and dark on markers of non-alcoholic fatty liver including liver fat index (FLI), lipid accumulation product (LAP), hepatic steatosis index (HSI), and Framingham steatosis index (FSI) in elderly women with type 2 diabetes.
Methods & Materials This quasi-experimental study was conducted on 45 elderly women with type 2 diabetes aged 60-65 years. Participants were randomly divided into three groups: control, training in the light phase (morning), and training in the dark phase (evening). Aerobic exercises were performed for 12 weeks, three sessions per week, and each session lasted 50 minutes at an intensity of 60-70% of maximum heart rate. Anthropometric and serum indices were measured before and after the intervention, and data were analyzed using analysis of covariance and paired t-tests.
Results The results demonstrated that both exercise groups exhibited a significant decrease in FLI, LAP, HSI, and FSI compared to the control group (P=0.001). Additionally, training in the dark phase demonstrated a more pronounced effect on reducing the LAP index than training in the light phase (P=0.002).
Conclusion Aerobic exercise scheduling can be an important factor in improving liver health in people with type 2 diabetes.
Methods & Materials This quasi-experimental study was conducted on 45 elderly women with type 2 diabetes aged 60-65 years. Participants were randomly divided into three groups: control, training in the light phase (morning), and training in the dark phase (evening). Aerobic exercises were performed for 12 weeks, three sessions per week, and each session lasted 50 minutes at an intensity of 60-70% of maximum heart rate. Anthropometric and serum indices were measured before and after the intervention, and data were analyzed using analysis of covariance and paired t-tests.
Results The results demonstrated that both exercise groups exhibited a significant decrease in FLI, LAP, HSI, and FSI compared to the control group (P=0.001). Additionally, training in the dark phase demonstrated a more pronounced effect on reducing the LAP index than training in the light phase (P=0.002).
Conclusion Aerobic exercise scheduling can be an important factor in improving liver health in people with type 2 diabetes.
Keywords: Circadian rhythms, Diabetes mellitus, Hepatic steatosis index, Liver fat index, Lipid accumulation product
Type of Study: Research |
Subject:
Rehabilitation Management
Received: 2025/01/29 | Accepted: 2025/09/29 | Published: 2026/04/01
Received: 2025/01/29 | Accepted: 2025/09/29 | Published: 2026/04/01
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